Doctoral Thesis: "Prediction of Thyroid interacting effects by new approach methodologies" (m/f/d)
Ludwigshafen am Rhein
Our Bioscience Research Division works on innovative and sustainable solutions for our customers in sectors, such as the agricultural sector or food industry. Our goal is to improve the quality of life and protect the environment through bioscience. Our creative and diverse team embodies mutual respect and develops market-driven innovations, which make our customers successful. Join our unit Experimental Toxicology and Ecology as a Ph.D. student starting in Q1/2022. During the 36-month Ph.D. project you will work on the topic "Analysis of Thyroid Toxicity Data by integrative approach to testing and assessment (IATA)". As a Ph.D. student you will be part of a highly motivated team in an international setting that focuses on in vitro toxicology and biokinetics. You will work on one of the most emerging topics in toxicology - the investigation of endocrine effects. Therefore, you will be trained in different in vitro assays to predict thyroid interacting effects and you will conduct hands-on research to further develop, adapt as well as improve methods and expand the data base of reference chemicals. Furthermore, you will assess the data also from a kinetic perspective by e.g. PBPK modelling. Evaluating the appropriate combination of different assays to predict the biological relevance of thyroid interacting effects will be another one of your exciting tasks. Besides, you will summarize the data in several manuscripts to be submitted in peer-review journals. Your contribution is an important aspect of the hazard and risk assessment of chemicals with potential endocrine properties and will help us to ensure the safe use of innovative products. graduate degree in toxicology, pharmacy, biology, biochemistry, or related disciplines experience in cell culture experiments (different mammalian cell lines) and know-how in different biological/toxicological readouts like fluorometric/luminometric measurements and imaging technologies ideally some experience and interest in mathematics and statistics; R know-how is preferable sound English and German language skills to be able to clearly communicate scientific results to an interdisciplinary team motivated and creative team player with a keen interest in exploring a broad range of topics From day one you will be part of the BASF family. You will get involved in challenging fields of activity and have the opportunity to work on exciting projects in an interdisciplinary environment. Depending on the location of the respective group company you will get to know BASF and participate in various workshops and guided tours. In this way you will make numerous interesting experiences and get a deep insight into the world's leading chemical company.
Head of Quality Assurance Unit (m/f/d)
Ludwigshafen am Rhein
Head of Quality Assurance Unit (m/f/d) Our Bioscience Research Division works on innovative and sustainable solutions for our customers in sectors, such as the agricultural sector or food industry. Our goal is to improve the quality of life and protect the environment through bioscience. Our creative and diverse team embodies mutual respect and develops market-driven innovations, which make our customers successful. LOCATION Ludwigshafen, DE COMPANY BASF SE WORKING HOURS Full-time CONTRACT TYPE Permanent WORKING AREA Toxicology / Product Safety REFERENCE CODE EN59964938_ONLE_1 For our department Experimental Toxicology and Ecology we are looking for a committed Head of Quality Assurance Unit who will be responsible for the maintenance, the monitoring, and the update of our Quality Assurance Program with direct responsibility to the management. You are in charge of enforcing the compliance with international GLP guidelines (OECD, ChemG, EPA) via regular internal and external facility and study-based inspections. You lead and manage a team of several quality assurance employees and you will conduct GLP training for new personnel and disseminate new GLP information. Besides, you represent BASF in national and international panels on quality assurance and GLP topics. Moreover, you will be the main contact for external audits by sponsors/ clients and inspections by authorities. Further responsibilities in this position include the cooperation with our service and contract management unit tensure the quality compliance of CROs and suppliers/ vendors. You are alsresponsible for our IS17020 program, and you will support implementation of digital tools in our GLP-environment. university degree in Biological Sciences, Chemistry, or equivalent qualification experience with managing and implementing a quality assurance program in a laboratory context as well as good laboratory practice procedures for non-clinical testing ability to work on schedule with high sense of responsibility as well as leadership and management skills experience with implementation of digital tools in a GLP-environment and ideally experience with ISO-systems like 17020 or 17025 enjoy working in interdisciplinary collaboration as well as good English written and verbal communication skills Development discussions and programs so that you can reach your full potential Onboarding to help you settle in quickly, ensuring you are part of the BASF team from day one. An attractive competitive salary that is based on the company's success and your individual performance. Flexible work arrangements so that you can balance your working life and private life